Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH05-59] to Human CD200 (Capture) (HA722379) and recombinant standard Human CD200 protein (HA210665). The reference range value is 30.9-2500pg/ml.
靶点
功能
This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms.
背景文献
1. Gorczynski R., Chen Z., Kai Y., Lee L., Wong S., Marsden P.A. CD200 is a ligand for all members of the CD200R family of immunoregulatory molecules. J. Immunol. 172:7744-7749 (2004).
2. Minas K., Liversidge J. Is the CD200/CD200 receptor interaction more than just a myeloid cell inhibitory signal? Crit Rev Immunol 26:213-230 (2006).