GDF15 Rabbit Polyclonal Antibody
Catalog# ER1909-46
GDF15 Rabbit Polyclonal Antibody
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WB
-
Mouse
-
Rat
-
unconjugated
概述
产品名称
GDF15 Rabbit Polyclonal Antibody
抗体类型
Rabbit Polyclonal Antibody
免疫原
KLH conjugated synthetic peptide derived from human GDF-15: 221-308/308
种属反应性
Mouse, Rat
验证应用
WB
分子量
12.5/34 kDa
阳性对照
Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney.
偶联
unconjugated
产品特性
形态
Liquid
浓度
存放说明
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
存储缓冲液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
亚型
IgG
纯化方式
Protein A affinity purified.
应用稀释度
-
WB
-
1:500-1:2,000
靶点
功能
Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues. GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.
背景文献
暂无
亚细胞定位
Secreted.
别名
GDF 15 antibody
GDF-15 antibody
Gdf15 antibody
GDF15_HUMAN antibody
Growth differentiation factor 15 antibody
Growth/differentiation factor 15 antibody
Macrophage inhibitory cytokine 1 antibody
MIC 1 antibody
Mic-1 antibody
MIC1 antibody
展开图片
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25 ug total protein per lane of various lysates (see on figure) probed with GDF15 polyclonal antibody, unconjugated (ER1909-46) at 1:1,000 dilution and 4℃ overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
同靶点 & 同通路的产品
GDF15 Recombinant Rabbit Monoclonal Antibody [JE39-90]
Application: WB
Reactivity: Human
Conjugate: unconjugated
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