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Anti-beta Tubulin Recombinant Rabbit Monoclonal Antibody [SR25-04]

重组兔单抗 | 货号: ET1602-4


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价格:RMB   1500
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  • 概述

  • 产品描述 Tubulin is one of several members of a small family of globular proteins. The most common members of the tubulin family are α-tubulin and β-tubulin. The beta-tubulin (relative molecular weight about 50 kDa) is counterpart of alpha-tubulin in tubulin heterodimer, it is coded by multiple tubulin genes and it is also posttranslationally modified. Heterogeneity of subunit is concentrated in C-terminal structural domain. Beta-Tubulin may have bound GTP or GDP. Under certain conditions β-tubulin can hydrolyze its bound GTP to GDP plus Pi, release the Pi, and exchange the GDP for GTP.
  • 产品名称 Anti-beta Tubulin Recombinant Rabbit Monoclonal Antibody [SR25-04]
  • 分子量 Predicted band size: 50 kDa
  • 种属反应性 Human,Mouse,Rat
  • 验证应用 WB,ICC,IHC-P,FC
  • 抗体类型 重组兔单抗
  • 免疫原 Synthetic peptide within Human beta Tubulin aa 308-357 / 444.
  • 偶联 Non-conjugated
  • 性能

  • 形态 Liquid
  • 浓度 1 mg/mL.
  • 存放说明 Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • 存储缓冲液 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • 亚型 IgG
  • 纯化方式 Protein A affinity purified.
  • 亚细胞定位 Cytoplasm
  • 数据链接 SwissProt: P07437 Human
    SwissProt: P99024 Mouse
    SwissProt: P69897 Rat
  • 其它名称
    • Beta 4 tubulin antibody
    • Beta 5 tubulin antibody
    • BetaTubulin antibody
  • 应用

    WB: 1:500
    ICC: 1:50
    IHC-P: 1:100-400
    FC: 1:50

  • 背景文献

  • 1. "Tumoral and tissue-specific expression of the major human beta-tubulin isotypes."Leandro-Garcia L.J., Leskela S., Landa I., Montero-Conde C., Lopez-Jimenez E., Leton R., .Cytoskeleton 67:214-223(2010).

    2. "Five mouse tubulin isotypes and their regulated expression during development."Lewis S.A., Lee M.G.-S., Cowan N.J.J. Cell Biol. 101:852-861(1985).
  • Publishing research using Anti-beta Tubulin Recombinant Rabbit Monoclonal Antibody? Please let us know so that we can cite the reference in this datasheet.

  • PMID:
    35408869
    Toward a Treatment of Cancer: Design and In Vitro/In Vivo Evaluation of Uncharged Pyrazoline Derivatives as a Series of Novel SHP2 Inhibitors Author: Dai, J., Zhang, Y., Gao, Y., Bai, X., Liu, F., Li, S., Yu, Y., Hu, W., Shi, T., Shi, D., & Li, X. Published: 2022 Application: WB Species: Human Journal: Int J Mol Sci IF: 5.924

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols