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Anti-PINK1 antibody

兔多抗 | 货号: ER1706-27


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  • 概述

  • 产品描述 A member of the serine / threonine protein kinase family, PTEN induced putative kinase 1 (PINK1) is a tumor suppressor. PINK1 is primarily located in mitochondria, and is ubiquitously expressed in testis, skeletal muscle, and heart tissue. at lower levels in pancreas, ovary, brain, placenta, kidney, liver, prostate and small intestine. During cellular stress PINK1 protects against mitochondrial dysfunction by inducing phosphorylation mitochondrial proteins. PINK1 mutations may give rise to different autophosphorylation activity. Mutations in the PINK1 gene (PARK6) are associated with early onset Parkinson's disease, a recessive neurodegenerative disorder characterized by resting tremor, muscular rigidity, bradykinesia and postural instability. Parkinson's disease generally involves the presence of intraneuronal accumulations of aggregated proteins (Lewy bodies) in brain neurons.
  • 产品名称 Anti-PINK1 antibody
  • 分子量 63 kDa
  • 种属反应性 Human, Mouse
  • 验证应用 WB,ICC,IHC-P
  • 抗体类型 兔多抗
  • 免疫原 Recombinant protein within human PINK1 aa 126-320.
  • 偶联 Non-conjugated
  • 性能

  • 形态 Liquid
  • 浓度 1 mg/mL.
  • 存放说明 Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • 存储缓冲液 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
  • 亚型 IgG
  • 纯化方式 Protein affinity purified.
  • 亚细胞定位 Mitochondrion outer membrane. Cytoplasm.
  • 数据链接 Q9BXM7 Human
    Q99MQ3 Mouse
  • 其它名称
    • BRPK antibody
    • FLJ27236 antibody
    • mitochondrial antibody
  • 应用

    WB: 1:500-1:1,000
    ICC: 1:50-1:200
    IHC-P: 1:100-1:200

  • 背景文献

  • 暂无
  • Publishing research using Anti-PINK1 antibody? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols