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Anti-Thymidine Kinase 1 antibody [JF0970]

重组兔单抗 | 货号: ET1702-31


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价格:RMB   1500
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  • 概述

  • 产品描述 Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells. Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5'-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA. Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is is also used to select hybridoma cell lines in the production of monoclonal antibodies. Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division. Because of this, Thymidine Kinase can be used as a proliferation marker in the diagnosis, treatment, and follow-up of malignant diseases, especially hematological malignancies. Thymidine Kinase may be observed as a monomer, dimer, trimer or tetramer.
  • 产品名称 Anti-Thymidine Kinase 1 antibody [JF0970]
  • 分子量 25 kDa
  • 种属反应性 Human,Mouse
  • 验证应用 WB, ICC/IF, IHC-P, IP, FC
  • 抗体类型 重组兔单抗
  • 免疫原 Synthetic peptide within Human Thymidine Kinase 1 aa 2-49 / 234.
  • 偶联 Non-conjugated
  • 性能

  • 形态 Liquid
  • 浓度 1 mg/mL.
  • 存放说明 Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • 存储缓冲液 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • 亚型 IgG
  • 纯化方式 Protein A affinity purified.
  • 亚细胞定位 Cytoplasm.
  • 数据链接 SwissProt: P04183 Human
    SwissProt: P04184 Mouse
  • 其它名称
    • cytosolic antibody
    • KITH_HUMAN antibody
    • Thymidine kinase 1 antibody
  • 应用

    WB: 1:1,000
    ICC/IF: 1:50-1:200
    IHC-P: 1:50-1:200
    FC: 1:50-1:100

  • 背景文献

  • 1. Breitbach CJ et al. Oncolytic vaccinia virus disrupts tumor-associated vasculature in humans. Cancer Res 73:1265-75 (2013).

    2. Viel T et al. Early assessment of the efficacy of temozolomide chemotherapy in experimental glioblastoma using [18F]FLT-PET imaging. PLoS One 8:e67911 (2013).
  • Publishing research using Anti-Thymidine Kinase 1 antibody? Please let us know so that we can cite the reference in this datasheet.

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols