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Developmental Biology - Lineage Specification

谱系规范是指在发育中的有机体中,一种多能细胞类型被导向一种特定的细胞命运的过程。解析每个细胞在这一过程中的完整发育历程(即“谱系”)是发育生物学领域的重要目标之一。谱系的研究有助于人们理解生命个体的发育,解析发育相关疾病的发病机制,并为基于细胞治疗的再生医学研究中不同类型细胞药物的体外分化和制备,提供关键依据和线索。

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