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Anti-Myc Tag Mouse Monoclonal Antibody [A3-B4]

小鼠单抗 | 货号: EM31105


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价格:RMB   1500
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  • 概述

  • 产品描述 Myc gene encodes for a transcription factor that is believed to regulate expression of 15% of all genes through binding on Enhancer Box sequences (E-boxes) and recruiting histone acetyltransferases (HATs). c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. This Myc-Tag antibody detects Myc-tagged fusion proteins.
  • 产品名称 Anti-Myc Tag Mouse Monoclonal Antibody [A3-B4]
  • 验证应用 WB,IF-Cell,ELISA,FC,IP
  • 抗体类型 小鼠单抗
  • 免疫原 Synthetic peptide immune sequence is EQKLISEEDLC-KLH.
  • 偶联 Non-conjugated
  • 性能

  • 形态 Liquid
  • 浓度 2 mg/mL.
  • 存放说明 Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • 存储缓冲液 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • 亚型 IgG2b
  • 纯化方式 Protein G affinity purified.
  • 其它名称
    • avian myelocytomatosis viral oncogene homolog antibody
    • bHLHe39 antibody
    • c-Myc antibody
  • 应用

    WB: 1:2,000
    IF-Cell: 1:50
    FC: 1:50-1:100
    IP: 2-5 µg/ml.

  • 背景文献

  • 1. "A quantitative atlas of mitotic phosphorylation."Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008)

    2. "Transactivation of gene expression by Myc is inhibited by mutation at the phosphorylation sites Thr-58 and Ser-62."Gupta S., Seth A., Davis R.J. Proc. Natl. Acad. Sci. U.S.A. 90:3216-3220(1993)
  • Publishing research using Anti-Myc Tag Mouse Monoclonal Antibody? Please let us know so that we can cite the reference in this datasheet.

  • PMID:
    35800772
    LncNSPL facilitates influenza A viral immune escape by restricting TRIM25-mediated K63-linked RIG-I ubiquitination Author: Jiang, J., Li, Y., Sun, Z., Gong, L., Li, X., Shi, F., Yao, J., Meng, Y., Meng, X., Zhang, Q., Wang, Y., Su, X., & Diao, H. Published: 2022 Application: WB Journal: iScience IF: 5.458
  • PMID:
    35806389
    CDK1 Promotes Epithelial-Mesenchymal Transition and Migration of Head and Neck Squamous Carcinoma Cells by Repressing ∆Np63α-Mediated Transcriptional Regulation Author: Chen, H., Hu, K., Xie, Y., Qi, Y., Li, W., He, Y., Fan, S., Liu, W., & Li, C. Published: 2022 Application: WB Journal: Int J Mol Sci. IF: 5.924
  • PMID:
    36314827
    IRF2 Cooperates with Phosphoprotein of Spring Viremia of Carp Virus to Suppress Antiviral Response in Zebrafish Author: Huang, W., Zhao, X., Ji, N., Guo, J., Feng, J., Chen, K., Wu, Y., Wang, J., Feng, H., & Zou, J. Published: 2022 Application: WB Species: Zebrafish Journal: Oncologist. IF: 5.837
  • PMID:
    33469231
    Site-1 protease controls osteoclastogenesis by mediating LC3 transcription. Cell death and differentiation, 28(6), 2001–2018. Author: Zheng, Z., Zhang, X., Huang, B., Liu, J., Wei, X., Shan, Z., Wu, H., Feng, Z., Chen, Y., Fan, S., Zhao, F., & Chen, J. Published: 2021 Application: WB,IF,IP Species: Mouse Journal: Cell Death Differ IF: 10.717
  • PMID:
    30366764
    Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages Author: 王迪 Published: 2018 Application: WB Species: None Journal: Immunity. IF: 19.734

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols