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Anti-Beta Actin Rabbit Polyclonal Antibody

兔多抗 | 货号: R1207-1


价格:RMB   1200


  • 概述

  • 产品描述 Actins are highly conserved proteins involved in cell motility, structure and integrity. Actin has been found to be expressed in at least six isomeric forms. It is expressed in heart and skeletal striated muscle tissue, and in certain smooth muscle tissues, regulating contractile potentials for these cells. It is also expressed in the cytoplasm of non-muscle cells, functioning to control cell structure and motility. Beta actin is usually used as a loading control, for among others, the integrity of cells, protein degradation, in Western Blotting.
  • 产品名称 Anti-Beta Actin Rabbit Polyclonal Antibody
  • 分子量 Predicted band size: 42 kDa
  • 种属反应性 Human,Mouse,Rat,Zebrafish,bamboo
  • 验证应用 WB,IF-Cell,IHC-P,FC
  • 抗体类型 兔多抗
  • 免疫原 Synthetic peptide within N-terminal residues of β-Actin.
  • 偶联 Non-conjugated
  • 性能

  • 形态 Liquid
  • 浓度 1 mg/mL.
  • 存放说明 Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
  • 存储缓冲液 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
  • 亚型 IgG
  • 纯化方式 Immunogen affinity purified.
  • 亚细胞定位 Cytoskeleton
  • 数据链接 SwissProt: P60709 Human
    SwissProt: P60710 Mouse
    SwissProt: P60711 Rat
    SwissProt: Q7ZVI7 Zebrafish
  • 其它名称
    • A26C1A antibody
    • A26C1B antibody
    • ACTB antibody
  • 应用

    WB: 1:10,000

  • 背景文献

  • 1. Ponte P., Ng S.Y., Engel J., Gunning P., Kedes L."Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA." Nucleic Acids Res. 12:1687-1696(1984) Ohmori H., Toyama S., Toyama S."Direct proof that the primary site of action of cytochalasin on cell motility processes is actin."J. Cell Biol. 116:933-941(1992)
  • Publishing research using Anti-Beta Actin Rabbit Polyclonal Antibody? Please let us know so that we can cite the reference in this datasheet.

  • PMID:
    Discovery of a potent and selective allosteric inhibitor targeting the SHP2 tunnel site for RTK-driven cancer treatment Author: Luo, R., Fu, W., Shao, J., Ma, L., Shuai, S., Xu, Y., Jiang, Z., Ye, Z., Zheng, L., Zheng, L., Yu, J., Zhang, Y., Yin, L., Tu, L., Lv, X., Li, J., Liang, G., & Chen, L. Published: 2023 Application: WB Species: Human Journal: Eur J Med Chem IF: 7.088
  • PMID:
    Assessment of Nonalcoholic Fatty Liver Disease Symptoms and Gut-Liver Axis Status in Zebrafish after Exposure to Polystyrene Microplastics and Oxytetracycline, Alone and in Combination Author: Zhou, W., Shi, W., Du, X., Han, Y., Tang, Y., Ri, S., Ju, K., Kim, T., Huang, L., Zhang, W., Yu, Y., Tian, D., Yu, Y., Chen, L., Wu, Z., & Liu, G. Published: 2023 Application: WB Species: Zebrafish Journal: Environ Health Perspect IF: 11.035
  • PMID:
    Maternal consumption of a fermented diet protects offspring against intestinal inflammation by regulating the gut microbiota Author: Wang, C., Wei, S., Liu, B., Wang, F., Lu, Z., Jin, M., & Wang, Y. Published: 2022 Application: WB Species: Pig Journal: Gut Microbes IF: 10.245
  • PMID:
    Nucleolar GTPase Bms1 displaces Ttf1 from RFB-sites to balance progression of rDNA transcription and replication Author: Zhu, Y., Wang, Y., Tao, B., Han, J., Chen, H., Zhu, Q., Huang, L., He, Y., Hong, J., Li, Y., Chen, J., Huang, J., Lo, L. J., & Peng, J. Published: 2022 Application: WB Species: Zebrafish Journal: J Mol Cell Biol IF: 6.216
  • PMID:
    Trehalose Attenuates Oxidative Stress and Endoplasmic Reticulum Stress-Mediated Apoptosis in IPEC-J2 Cells Subjected to Heat Stress Author: Mo, F., Zhou, X., Yang, M., Chen, L., Tang, Z., Wang, C., & Cui, Y. Published: 2022 Application: WB Species: Pig Journal: Animals (Basel). IF: 3.231
  • PMID:
    Lactobacillus plantarum postbiotics trigger AMPK-dependent autophagy to suppress Salmonella intracellular infection and NLRP3 inflammasome activation Author: Wu, Y., Hu, A., Shu, X., Huang, W., Zhang, R., Xu, Y., & Yang, C. Published: 2022 Application: WB Species: Pig Journal: J Cell Physiol . IF: 6.513
  • PMID:
    Phellinus baumii Polyphenol: A Potential Therapeutic Candidate against Lung Cancer Cells Author: Liu, X., Cui, S., Dan, C., Li, W., Xie, H., Li, C., & Shi, L. Published: 2022 Application: WB Species: Human Journal: Int J Mol Sci. IF: 6.208
  • PMID:
    Streptococcus pneumoniae promotes migration and invasion of A549 cells in vitro by activating mTORC2/AKT through up-regulation of DDIT4 expression Author: Song, X., Liu, B., Zhao, G., Pu, X., Liu, B., Ding, M., & Xue, Y. Published: 2022 Application: WB Species: Human Journal: Front Microbiol. IF: 6.064
  • PMID:
    HRG-9 homologues regulate haem trafficking from haem-enriched compartments Author: Sun, F., Zhao, Z., Willoughby, M. M., Shen, S., Zhou, Y., Shao, Y., Kang, J., Chen, Y., Chen, M., Yuan, X., Hamza, I., Reddi, A. R., & Chen, C. Published: 2022 Application: WB Species: Mouse Journal: Nature IF: 69.504
  • PMID:
    Multi-omics analysis identifies potential mechanisms of AURKB in mediating poor outcome of lung adenocarcinoma. Aging, 13(4), 5946–5966. Author: Huang, J., Zhang, Q., Shen, J., Chen, X., & Ma, S. Published: 2021 Application: WB Species: Human Journal: Aging (Albany NY)
  • PMID:
    FHL1 Inhibits the Progression of Colorectal Cancer by Regulating the Wnt/β-Catenin Signaling Pathway. Journal of Cancer, 12(17), 5345–5354. Author: Liu, Y., Wang, C., Cheng, P., Zhang, S., Zhou, W., Xu, Y., Xu, H., & Ji, G. Published: 2021 Application: WB Species: Human Journal: J Cancer IF: 4.204
  • PMID:
    Targeting CXCR2 inhibits the progression of lung cancer and promotes therapeutic effect of cisplatin. Molecular cancer, 20(1), 62. Author: Cheng, Y., Mo, F., Li, Q., Han, X., Shi, H., Chen, S., Wei, Y., & Wei, X. Published: 2021 Application: WB Species: Mouse Journal: Mol Cancer
  • PMID:
    The N6-methyladenosine RNA-binding protein YTHDF1 modulates the translation of TRAF6 to mediate the intestinal immune response. Nucleic acids research, 49(10), 5537–5552. Author: Zong, X., Xiao, X., Shen, B., Jiang, Q., Wang, H., Lu, Z., Wang, F., Jin, M., Min, J., Wang, F., & Wang, Y. Published: 2021 Application: WB Species: Mouse Journal: Nucleic Acids Res IF: 16.971
  • PMCID:
    Kaempferol Alleviates Steatosis and Inflammation During Early Non-Alcoholic Steatohepatitis Associated With Liver X Receptor α-Lysophosphatidylcholine Acyltransferase 3 Signaling Pathway. Frontiers in pharmacology, 12, 690736. Author: Xiang, H., Shao, M., Lu, Y., Wang, J., Wu, T., & Ji, G. Published: 2021 Application: WB Species: Mouse Journal: Front Pharmacol
  • PMID:
    Circadian clock gene BMAL1 reduces urinary calcium oxalate stones formation by regulating NRF2/HO-1 pathway. Life sciences, 265, 118853. Author: Wang, J., Bai, Y., Yin, S., Cui, J., Zhang, Y., Wang, X., Zhang, F., Li, H., Tang, Y., & Wang, J. Published: 2021
  • PMID:
    p53 isoform Δ113p53 promotes zebrafish heart regeneration by maintaining redox homeostasis Author: Wei-Qiang Tan;Jun Chen Published: 2020 Application: WB Species: Zebrafish Journal: Cell Death and Disease IF: 6.304
  • PMID:
    Metformin Prevents Follicular Atresia in Aging Laying Chickens through Activation of PI3K/AKT and Calcium Signaling Pathways Author: Jian Li; Caiqiao Zhang Published: 2020 Application: WB,IF,IHC Species: hen Journal: Oxid Med Cell Longev. IF: 5.076
  • PMID:
    Liver injury in septic mice were suppressed by a camptothecin-bile acid conjugate via inhibiting NF-κB signaling pathway. Life sciences, 257, 118130. Author: Xiao, L. X., Qi, L., Zhang, X. L., Zhou, Y. Q., Yue, H. L., Yu, E. D., & Li, Q. Y. Published: 2020 Application: WB Species: Mouse Journal: Life Sciences IF: 3.647
  • PMID:
    Chronic mild hypoxia promotes hippocampal neurogenesis involving Notch1 signaling in epileptic rats. Author: Weiping Wang,Junli Zhen Published: 2019 Application: WB Species: rat Journal: Brain Res. IF: 2.929
  • PMID:
    Production and Function of Different Regions from Mytichitin-1 of Mytilus coruscus Author: Liao Zhi Published: 2019 Application: WB Species: Mytilus coruscus Journal: Fish Shellfish Immunol. IF: 3.185
  • PMID:
    Selective Killing of Cancer Cells by Nonplanar Aromatic Hydrocarbon-Induced DNA Damage Author: Huibin Qiu;Peifeng Liu Published: 2019 Application: WB Species: human Journal: Adv Sci (Weinh). IF: 15.804
  • PMID:
    Histone H3K9 demethylase JMJD1A is a co-activator of erythropoietin expression under hypoxia. Author: Xiaoqiang Guo ,Xianglin Duan Published: 2019 Application: WB Species: hepatocellular carcinoma cells (HepG2) Journal: Int J Biochem Cell Biol. IF: 3.144
  • PMID:
    Zebrafish slc30a10 deficiency revealed a novel compensatory mechanism of Atp2c1 in maintaining manganese homeostasis Author: Wang F Published: 2018 Application: WB Species: Zebrafish Journal: PLoS Genet. IF: 6.1
  • PMID:
    Inhibition of MyD88 Signaling Skews Microglia/Macrophage Polarization and Attenuates Neuronal Apoptosis in the Hippocampus After Status Epilepticus in Mice Author: Hua Zhang; Fang Kuang Published: 2018 Application: WB Species: mouse Journal: Neurotherapeutics. IF: 5.719
  • PMID:
    Liver-Enriched Gene 1,a Glycosylated Secretory Protein,Binds to FGFR and Mediates an Anti-stress Pathway to Protect Liver Development in Zebrafish Author: Jinrong Peng Published: 2016 Application: IF Species: Zebrafish Journal: PLOS Genetics IF: 6.7
  • PMID:
    Immune response of peroxinectin of chinese mitten crab eriocheir sinensis to exterior stimulation Author: Yuyin Chen Published: 2015 Application: WB Species: Eriocheir sinensis Journal: Dev Comp Immunol IF: 3.218
  • PMID:
    Cancer-Associated Fibroblasts in a Human HEp-2 Established Laryngeal Xenografted Tumor Are Not Derived from Cancer Cells through Epithelial-Mesenchymal Transition,Phenotypically Activated but Karyotypically Normal Author: Guo-Kang Fan Published: 2015 Application: WB Species: human Journal: PLoS One IF: 3.2
  • PMID:
    Autophagy inhibits chemotherapy-induced apoptosis through downregulating Bad and Bim in hepatocellular carcinoma cells Author: Lixin Weib Published: 2014 Application: WB Species: human Journal: Sci Rep IF: 5.6
  • PMID:
    Autophagy protects against palmitate-induced apoptosis in hepatocytes Author: Lixin Wei Published: 2014 Application: WB Species: human Journal: Cell Biosci IF: 3.6
  • PMID:
    Identification of Cancer Stem-Like Side Population Cells in Purified Primary Cultured Human Laryngeal Squamous Cell Carcinoma Epithelia Author: Jin-Yan Li Published: 2013 Application: WB Species: human Journal: PLoS One IF: 3.5

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Specific Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

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